Research course

Neuroscience

Institution
Queen Mary, University of London · School of Medicine and Dentistry
Qualifications
PhD

Entry requirements

For entry to a PhD programme you should hold either; A first or upper second class honours degree in a relevant biological subject from a UK university A Masters degree A recognised equivalent from an accredited overseas institution An equivalent professional qualification.

Months of entry

September

Course content

The Centre has sixteen academic staff and research is focused on three interrelated topics: Trauma; Neuroinflammation and pain; Neuro-oncology and genomics.

Trauma
The focus of our research is on spinal cord and peripheral nerve injury and coagulation. The Trauma group has identified several therapeutic strategies to prevent complications of injury, and to limit and repair its damage.

Neuroinflammation and pain
The main disease focus of the Neuroimmunology group is multiple sclerosis. Research is currently focused on immune tolerance strategies, the development of neuroprotective and neurorestorative therapies for progressive multiple sclerosis and the manipulation of the endocannabinoid biology as a therapeutic strategy to improve the symptoms of multiple sclerosis.

Neuro-oncology and genomics
Our research includes:

  • a molecular and developmental biology approach in mouse models that shows how cellular and molecular mechanisms control the development of the central nervous system and can contribute to brain tumorigenesis when deregulated
  • a study of the function of human chromosomes and the genetic basis of cancer, with the discovery of distinct higher order chromatin configurations and loop domains that are dependent on gene density and transcriptional activity. Research also focuses on critical pathways involved in tumorigenesis, with an emphasis on brain tumours.

There are also active research programmes in motor neurone disease, pain, muscle regeneration, biomarkers and clinical outcomes.

Future objectives for the Centre include the establishment of research and clinical units in spinal injury, preventative neurology and neuroinfectious diseases and further development of basic research in CNS tumour biology.

Department specialisms

Neuronal Plasticity; Nerve Injury; Growth Factors; Developmental Biology; Neuropharmacology; Voltametry; Chemical Neuroanatomy

Fees and funding

BBSRC.

Qualification and course duration

PhD

full time
36 months

Course contact details

Name
Prof J V Priestley
Email
j.v.priestley@qmw.ac.uk
Phone
020 7882 6343
Fax
020 7882 7726