Research course

Gene Expression

The University of Manchester · Faculty of Life Sciences

Entry requirements

The standard entry requirement for MPhil study is a First or Upper Second class honours degree, or the overseas equivalent, in a relevant subject. In certain circumstances, a Lower Second class honours degree supplemented by appropriate relevant experience, may be acceptable. For PhD, in certain circumstances, a Lower Second class honours degree supplemented by a Masters degree, or appropriate relevant work experience, may be acceptable.

Months of entry

January, April, July, September

Course content

Manchester is a major centre for research in gene expression and intracellular signalling. Gene expression can be divided into three main events, beginning with the transcription of a gene to produce an RNA precursor. This is processed to produce a mature mRNA that is then translated to produce the protein product. Members of the group are engaged in the study of all of these events at the molecular, cellular and organismal levels. Gene expression is stringently regulated and is the end point of many intracellular signalling cascades. Several members of the group are interested in the mechanisms of signal transduction and how they mediate specific responses in gene expression profiles. A range of processes are under investigation, including development, cancer, stress response and biological clocks. A variety of model organisms/systems are used, from yeast to mammals, to study different aspects of gene expression including signal transduction, chromatin, transcriptional regulation, RNA processing/biology and translation.

Information for international students

Applicants whose first language is not English an IELTS score of 6.5, TOEFL 577 (paper based), TOEFL 233 (computer based) or TOEFL 90 (internet based) is required as a minimum.

Fees and funding

Faculty of Life Sciences - Various Studentships
Faculty of Life Sciences - Wellcome Trust Four Year PhD Studentships

Qualification and course duration


part time
72-96 months
full time
36-48 months


part time
24 months
full time
12 months

Course contact details

Faculty of Life Sciences Postgraduate Office
+44 (0) 161 275 5608
+44 (0) 161 275 5657