Research course

Stroke Medicine

Institution
University of Nottingham · Division of Stroke Medicine
Qualifications
PhDMPhilDM

Entry requirements

2:1 (or international equivalent) in an appropriate subject; candidates are generally required to submit a research proposal with their applications.

Months of entry

January, December, November, October, September, August, July, June, May, April, March, February

Course content

The clinical interests of the Division are in the treatment of acute stroke, enhancing recovery and preventing recurrence. The following multicentre trials are coordinated by Philip Bath & Niki Sprigg from the Stroke Trials Unit:

  • Ultra-acute lowering of blood pressure before hospitalisation (RIGHT trial)
  • Hyperacute cooling/hypothermia (EU FP-7 trial)
  • Hyperacute tranexamic acid for primary intracerebral haemorrhage (HTA TICH-2 trial)
  • Acute lowering of BP in hospital (MRC ENOS trial of glyceryl trinitrate)
  • Acute intensive antiplatelets for preventing early recurrence (BHF-HTA TARDIS trial)
  • Prevention of post stroke cognitive impairment (TSA-AS PODCAST trial)
  • Chronic mobilisation of endogenous stem cells (RfPB STEMS-3 trial of granulocyte colony stimulating factor)
  • Research projects are available in each of these studies. The Division of Stroke Medicine hosts the mid Trent part of the UK Stroke Research Network.


The translational studies, led by Dr Ulvi Bayraktutan, aim to identify a series of novel therapeutic targets that can subsequently be employed in clinical settings to prevent and/or reverse ischaemic injury-mediated breakdown of the blood-brain barrier and the ensuing formation of brain oedema which accounts for the majority of deaths within the first week after an ischaemic stroke. In this regard, the currently ongoing projects focus on

  • Pro-inflammatory cytokines, notably TNF-alpha and Interleukin-1beta,
  • NADPH oxidase enzyme system and oxidative stress,
  • Matrix metalloproteinases,
  • Plasminogen-plasmin system components,
  • Hypothermia.

For a more extensive overview, please visit the course page on the University of Nottingham's online prospectus.

Department specialisms

Causes of stroke. Acute treatment of patients after stroke. Prevention of recurrence stroke. Key words: Pathophysiology: Acute management: Recovery and rehabilitation.

Information for international students

English language requirements: IELTS 6.5 (no less than 6.0 in any element).

Fees and funding

The Graduate School at The University of Nottingham provides information on internal and external sources of postgraduate funding.

There is also funding information on the Medical School web pages.

For information on funding opportunities for international students, please see the International Office website.

Qualification and course duration

PhD

part time
72 months
full time
36 months

MPhil

full time
24 months
part time
48 months

DM

full time
36 months
part time
72 months

Course contact details

Name
PGT Administrator
Email
msctnir@nottingham.ac.uk
Phone
+44 (0)115 82 31765